Research

Antibody May Provide a Strategy Against Metastatic Bone Cancer

Posted by  | Research

An antibody drug that targets part of the bone growth pathway can slow the growth of human osteosarcoma implanted in mice and prevent the tumor from spreading to other parts of the body, according to a study led by Johns Hopkins Kimmel Cancer Center scientists. Osteosarcoma is one of the most common bone tumors affecting children(...)

Two Studies Uncover Potential Treatments for Lethal Pediatric Brain Cancer DIPG

Two Studies Uncover Potential Treatments for Lethal Pediatric Brain Cancer DIPG

Posted by  | Childhood Cancer, Research

A rare cell line developed by Johns Hopkins researchers is giving scientists their first chance in decades to test new therapies for a lethal pediatric brain cancer that has few treatments. Kimmel Cancer Center scientist Eric H. Raabe, M.D., Ph.D., helped to develop the diffuse intrinsic pontine glioma (DIPG) cell line, grown from tumor tissue donated by(...)

Can biomarkers predict patients’ response to immunotherapy?

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Immunotherapy expert, Suzanne Topalian, M.D., delivered a presentation to a standing room only crowd at the 2016 American Society of Clinical Oncology (#ASCO16) regarding new directions in scientists’ search for biomarkers that identify patients and tumor types most likely to respond to immunotherapy drugs. Among the approaches is an immunohistochemistry test for the protein PD-L1,(...)

ASCO annual meeting features clinical trial results of immunotherapy for bladder and kidney cancer

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With recent FDA approvals of immunotherapy drugs for kidney and bladder cancer, patients now have more options to consider among their treatments. The 2016 ASCO annual meeting featured several new developments in these two cancers that seem to keep the momentum moving forward in this field. We asked Charles Drake, M.D., Ph.D., associate director of(...)

Perspective on a breast cancer genome sequencing study

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In today's lineup of stories covered by WNYC's radio program The Takeaway, Kimmel Cancer Center expert Josh Lauring, M.D., Ph.D., provides his perspective on a new study published yesterday in the journal Nature by the Wellcome Trust Sanger Institute. The study is an analysis of the genomic sequencing of 560 breast cancer patients. Listen to Lauring and radio host John(...)

One-third of patients with metastatic melanoma treated with immunotherapy drug nivolumab survive five years

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At the 2016 American Association for Cancer Research annual meeting today, scientists presented their results of a follow-up study tracking the survival of metastatic melanoma patients who were treated with the immunotherapy drug nivolumab. The drug is currently approved by the U.S. Food and Drug Administration for advanced lung and kidney cancers and advanced melanomas.(...)

Shaping the Future of Cancer Research Training

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**This blog post was written by Kimmel Cancer Center development coordinator Allison Rich. Ben Park, M.D., Ph.D., was recently named the Johns Hopkins Kimmel Cancer Center’s associate director for research training and education. Already an internationally recognized physician-scientist committed to training and mentoring young students and faculty members, Park’s new role allows him to even(...)